Kanazawa University, Graduate School of Natural Science and Technology, Division of Mathematical and Physical Science
Biophysics
Type of organization
University and attached laboratory
Contact address
| Name of Organization |
|
Kanazawa University, Graduate School of Natural Science and Technology, Division of Mathematical and Physical Science Biophysics |
| Address |
|
Kakuma-machi, Kanazawa 920-1192, Ishikawa 920-1192
|
| URL |
|
|
| Phone |
|
076-264-5663 |
| Facsimile |
|
076-264-5739 |
member of laboratory
|
Leader
|
|
Professor |
|
Toshio Ando |
|
|
|
-
|
|
Associate Professor |
|
Takayuki Uchihashi |
|
|
Research field
|
C
|
Life science
|
| |
C2
|
The nanobiology
|
| |
( Scanning probe microscope )
|
|
|
biological nano-machine |
| |
F1
|
Measurement and evaluation technology
|
| |
( Scanning probe microscope The bio device Precision measurement )
|
|
F
|
"Measurement and evaluation, processing technology"
|
| |
F1
|
Measurement and evaluation technology
|
| |
( Scanning probe microscope Nano biology )
|
Research theme
| - |
Development of a highest-speed atomic force microscope and elucidation of the nano-structural dynamics of biological molecular motors |
Grant-in-aids for Scientific Research
|
| - |
Development of a high-speed AFM and Observation of protein dynamic behavior |
The large basic research promotion system
|
Purpose and background of research
Key Information that is lacking in understanding the mechanism of biological macromolecules is their structural dynamics. To gain the structural dynamics of biological macromolecules, a technique that has high spatial resolution as well as effective temporal resolution is most required.
Methodology and originality
It is only the atomic force micriscope that can image nanometer world in solution. However, its imaging rate is vely small, and therfore it can image only samples that are stational or moving very slowly. We developed for the first time a high-speed AFM that can capture a 100x100 pixel image within 80 ms. At present we are trying to enhance the capability of this AFM.
Major insturments
- High-speed atomic force microscope
- Scanning Electron Microscope
Result and impact
We developed an atomic force microscope that has the highest scanning speed, and succeeded in capturing moving molecules on video at 60 ms/frame.
-- Updated on : Jun 21, 2006 --